Tetrahydroquinazole-based secondary sulphonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IV, and IX, and computational studies

A library of variously decorated N-phenyl secondary sulphonamides featuring the bicyclic tetrahydroquinazole scaffold was synthesised and biologically evaluated for their inhibitory activity against human carbonic anhydrase (hCA) I, II, IV, and IX. Of note, several compounds were identified showing...

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Main Authors: Emma Baglini (Author), Rahul Ravichandran (Author), Emanuela Berrino (Author), Silvia Salerno (Author), Elisabetta Barresi (Author), Anna Maria Marini (Author), Monica Viviano (Author), Sabrina Castellano (Author), Federico Da Settimo (Author), Claudiu T. Supuran (Author), Sandro Cosconati (Author), Sabrina Taliani (Author)
Format: Book
Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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