GLP-1 improves the supportive ability of astrocytes to neurons by promoting aerobic glycolysis in Alzheimer's disease

• Main Authors: Jiaping Zheng (Author), Yunzhen Xie (Author), Lingjia Ren (Author), Liqin Qi (Author), Li Wu (Author), Xiaodong Pan (Author), Jianxing Zhou (Author), Zhou Chen (Author), Libin Liu (Author)
• Format: Book
• Published: Elsevier, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Astrocytes actively participate in energy metabolism in the brain, and astrocytic aerobic glycolysis disorder is associated with the pathology of Alzheimer's disease (AD). GLP-1 has been shown to improve cognition in AD; however, the mechanism remains unclear. The objectives of this...