Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection

The objective of our present study is to develop novel inhibitors for MMP-2 for acute cardioprotection. In a series of pilot studies, novel substituted carboxylic acid derivatives were synthesized based on imidazole and thiazole scaffolds and then tested in a screeening cascade for MMP inhibition. W...

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Detalhes bibliográficos
Main Authors: Péter Bencsik (Author), Krisztina Kupai (Author), Anikó Görbe (Author), Éva Kenyeres (Author), Zoltán V. Varga (Author), János Pálóczi (Author), Renáta Gáspár (Author), László Kovács (Author), Lutz Weber (Author), Ferenc Takács (Author), István Hajdú (Author), Gabriella Fabó (Author), Sándor Cseh (Author), László Barna (Author), Tamás Csont (Author), Csaba Csonka (Author), György Dormán (Author), Péter Ferdinandy (Author)
Formato: Livro
Publicado em: Frontiers Media S.A., 2018-04-01T00:00:00Z.
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