Development of Matrix Metalloproteinase-2 Inhibitors for Cardioprotection
The objective of our present study is to develop novel inhibitors for MMP-2 for acute cardioprotection. In a series of pilot studies, novel substituted carboxylic acid derivatives were synthesized based on imidazole and thiazole scaffolds and then tested in a screeening cascade for MMP inhibition. W...
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Main Authors: | , , , , , , , , , , , , , , , , , |
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Formato: | Livro |
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Frontiers Media S.A.,
2018-04-01T00:00:00Z.
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