Processing Parameters and Ion Excipients Affect the Physicochemical Characteristics of the Stereocomplex-Formed Polylactide-b-Polyethylene Glycol Nanoparticles and Their Pharmacokinetics

To optimize the characteristics of stereocomplex polylactide-b-polyethylene glycol nanoparticles (SC-PEG NPs) in terms of pharmacokinetics (PK), we chose continuous anti-solvent precipitation with a T-junction as a preparation method and investigated the effect of using solvents containing an ion ex...

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Main Authors: Kohei Ogawa (Author), Hidemasa Katsumi (Author), Yasushi Moroto (Author), Masaki Morishita (Author), Akira Yamamoto (Author)
Format: Book
Published: MDPI AG, 2022-03-01T00:00:00Z.
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3rd Floor Main Library

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