Mitochondrial ROS Induce Partial Dedifferentiation of Human Mesothelioma via Upregulation of NANOG

• Main Authors: Filip Sedlic (Author), Fran Seiwerth (Author), Ana Sepac (Author), Suncana Sikiric (Author), Marina Cindric (Author), Marija Milavic (Author), Lovorka Batelja Vuletic (Author), Marko Jakopovic (Author), Sven Seiwerth (Author)
• Format: Book
• Published: MDPI AG, 2020-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The expression of pluripotency factors is a key regulator of tumor differentiation status and cancer stem cells. The purpose of this study was to examine the expression of pluripotency factors and differentiation status of human mesothelioma and the role of mitochondria in their regulation. We teste...