The Extracellular Matrix Vitalizer RA^TM Increased Skin Elasticity by Modulating Mitochondrial Function in Aged Animal Skin

• Main Authors: Kyung-A Byun (Author), Seyeon Oh (Author), Sosorburam Batsukh (Author), Min Jeong Kim (Author), Je Hyuk Lee (Author), Hyun Jun Park (Author), Moon Suk Chung (Author), Kuk Hui Son (Author), Kyunghee Byun (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Oxidative stress-induced cellular senescence and mitochondrial dysfunction result in skin aging by increasing ECM levels-degrading proteins such as MMPs, and decreasing collagen synthesis. MMPs also destroy the basement membrane, which is involved in skin elasticity. The extracellular matrix vitaliz...