Carvacrol alleviates LPS-induced myocardial dysfunction by inhibiting the TLR4/MyD88/NF-κB and NLRP3 inflammasome in cardiomyocytes

• Main Authors: Lu Xu (Author), Xu Yang (Author), Xiao-Ting Liu (Author), Xia-Yun Li (Author), Han-Zhao Zhu (Author), Yan-Hua Xie (Author), Si-Wang Wang (Author), Yao Li (Author), Ye Zhao (Author)
• Format: Book
• Published: BMC, 2024-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sepsis-induced myocardial dysfunction (SIMD) may contribute to the poor prognosis of septic patients. Carvacrol (2-methyl-5-isopropyl phenol), a phenolic monoterpene compound extracted from various aromatic plants and fragrance essential oils, has multiple beneficial effects such...