Amorphous Solid Dispersion Tablets Overcome Acalabrutinib pH Effect in Dogs

Amorphous Solid Dispersion Tablets Overcome Acalabrutinib pH Effect in Dogs

Calquence<sup>®</sup> (crystalline acalabrutinib), a commercially marketed tyrosine kinase inhibitor (TKI), exhibits significantly reduced oral exposure when taken with acid-reducing agents (ARAs) due to the low solubility of the weakly basic drug at elevated gastric pH. These drug-drug...

Full description

Saved in:
Bibliographic Details
Main Authors: Deanna M. Mudie (Author), Aaron M. Stewart (Author), Jesus A. Rosales (Author), Nishant Biswas (Author), Molly S. Adam (Author), Adam Smith (Author), Christopher D. Craig (Author), Michael M. Morgen (Author), David T. Vodak (Author)
Format: Book
Published: MDPI AG, 2021-04-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items