A population pharmacodynamic Markov mixed‐effects model for determining remimazolam‐induced sedation when co‐administered with fentanyl in procedural sedation

• Päätekijät: Jie Zhou (Tekijä), Laura Curd (Tekijä), Lauren R. L. Lohmer (Tekijä), Natalie Delpratt (Tekijä), Joachim Ossig (Tekijä), Frank Schippers (Tekijä), Thomas Stoehr (Tekijä), Virginia D. Schmith (Tekijä)
• Aineistotyyppi: Kirja
• Julkaistu: Wiley, 2021-07-01T00:00:00Z.
• Aiheet: article
• Linkit: Connect to this object online.

ABSTRACT The clinical effects of remimazolam (an investigational, ultra‐short acting benzodiazepine being studied in procedural sedation) were measured using the Modified Observer's Assessment of Awareness/Sedation Scale (MOAA/S). The objective of this analysis was to develop a population pharm...