A population pharmacodynamic Markov mixed‐effects model for determining remimazolam‐induced sedation when co‐administered with fentanyl in procedural sedation

• Main Authors: Jie Zhou (Author), Laura Curd (Author), Lauren R. L. Lohmer (Author), Natalie Delpratt (Author), Joachim Ossig (Author), Frank Schippers (Author), Thomas Stoehr (Author), Virginia D. Schmith (Author)
• Format: Book
• Published: Wiley, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACT The clinical effects of remimazolam (an investigational, ultra‐short acting benzodiazepine being studied in procedural sedation) were measured using the Modified Observer's Assessment of Awareness/Sedation Scale (MOAA/S). The objective of this analysis was to develop a population pharm...