A population pharmacodynamic Markov mixed‐effects model for determining remimazolam‐induced sedation when co‐administered with fentanyl in procedural sedation

A population pharmacodynamic Markov mixed‐effects model for determining remimazolam‐induced sedation when co‐administered with fentanyl in procedural sedation

ABSTRACT The clinical effects of remimazolam (an investigational, ultra‐short acting benzodiazepine being studied in procedural sedation) were measured using the Modified Observer's Assessment of Awareness/Sedation Scale (MOAA/S). The objective of this analysis was to develop a population pharm...

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Main Authors: Jie Zhou (Author), Laura Curd (Author), Lauren R. L. Lohmer (Author), Natalie Delpratt (Author), Joachim Ossig (Author), Frank Schippers (Author), Thomas Stoehr (Author), Virginia D. Schmith (Author)
Format: Book
Published: Wiley, 2021-07-01T00:00:00Z.
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