New insight into the development of synpolydactyly caused by expansion of HOXD13 polyalanine based on weighted gene co-expression network analysis

• Main Authors: Xiumin Chen (Author), Xiaofang Shen (Author), Tao Yang (Author), Yixuan Cao (Author), Xiuli Zhao (Author)
• 格式: 图书
• 出版: BMC, 2024-10-01T00:00:00Z.
• 主题: article
• 在线阅读: Connect to this object online.

Abstract Background Synpolydactyly (SPD) is mainly caused by mutations of polyalanine expansion (PAE) in the transcription factor gene HOXD13 and the involved cell types and signal pathway are still not clear possible pathways and single-cell expression characteristics of limb bud in HOXD13 PAE mice...