Intelligent lesion blood-brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection

• Main Authors: Xueqin He (Author), Xiaorong Wang (Author), Lianyi Yang (Author), Zhihang Yang (Author), Wenqi Yu (Author), Yazhen Wang (Author), Rui Liu (Author), Meiwan Chen (Author), Huile Gao (Author)
• Format: Book
• Published: Elsevier, 2022-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The treatment of Alzheimer's disease (AD) is one of the most difficult challenges in neurodegenerative diseases due to the insufficient blood‒brain barrier (BBB) permeability and unsatisfactory intra-brain distribution of drugs. Therefore, we established an ibuprofen and FK506 encapsulated drug...