Intelligent lesion blood-brain barrier targeting nano-missiles for Alzheimer's disease treatment by anti-neuroinflammation and neuroprotection

• 主要な著者: Xueqin He (著者), Xiaorong Wang (著者), Lianyi Yang (著者), Zhihang Yang (著者), Wenqi Yu (著者), Yazhen Wang (著者), Rui Liu (著者), Meiwan Chen (著者), Huile Gao (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2022-04-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The treatment of Alzheimer's disease (AD) is one of the most difficult challenges in neurodegenerative diseases due to the insufficient blood‒brain barrier (BBB) permeability and unsatisfactory intra-brain distribution of drugs. Therefore, we established an ibuprofen and FK506 encapsulated drug...