Targeted Transfection Using PEGylated Cationic Liposomes Directed Towards P-Selectin Increases siRNA Delivery into Activated Endothelial Cells

• Main Authors: Cristina Ana Constantinescu (Author), Elena Valeria Fuior (Author), Daniela Rebleanu (Author), Mariana Deleanu (Author), Viorel Simion (Author), Geanina Voicu (Author), Virginie Escriou (Author), Ileana Manduteanu (Author), Maya Simionescu (Author), Manuela Calin (Author)
• Format: Book
• Published: MDPI AG, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<b>: </b>The progress in small-interfering RNA (siRNA) therapeutics depends on the development of suitable nanocarriers to perform specific and effective delivery to dysfunctional cells. In this paper, we questioned whether P-selectin, a cell adhesion molecule specifically expressed on t...