Intensive Glucose Control Reduces the Risk Effect of TRIB3, SMARCD3, and ATF6 Genetic Variation on Diabetic Vascular Complications

• Main Authors: Fazhong He (Author), Yan Shu (Author), Xingyu Wang (Author), Xin Liu (Author), Guojing Liu (Author), Zhangren Chen (Author), Zhenmin Wang (Author), Ling Li (Author), Rong Liu (Author), Honghao Zhou (Author), Heng Xu (Author), Wei Zhang (Author), Gan Zhou (Author)
• Format: Book
• Published: Frontiers Media S.A., 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Type 2 diabetes mellitus is a complex disease. Our previous study revealed that TRIB3 genetic variations were strongly associated with diabetic vascular complications, although TRIB3 regulation pathways remain poorly understood. We used two extreme treatment groups from a 2 × 2 factorial randomized...