Building bioorthogonal click-release capable artificial receptors on cancer cell surface for imaging, drug targeting and delivery

• Autors principals: Jing Chen (Autor), Peng Ji (Autor), Giri Gnawali (Autor), Mengyang Chang (Autor), Feng Gao (Autor), Hang Xu (Autor), Wei Wang (Autor)
• Format: Llibre
• Publicat: Elsevier, 2023-06-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

The current targeting drug delivery mainly relies on cancer cell surface receptors. However, in many cases, binding affinities between protein receptors and homing ligands is relatively low and the expression level between cancer and normal cells is not significant. Distinct from conventional target...