Repeated Aconitine Treatment Induced the Remodeling of Mitochondrial Function via AMPK-OPA1-ATP5A1 Pathway

• Main Authors: Li-Zhen Qiu (Author), Wei Zhou (Author), Lan-Xin Yue (Author), Yi-Hao Wang (Author), Fei-Ran Hao (Author), Peng-Yan Li (Author), Yue Gao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Aconitine is attracting increasing attention for its unique positive inotropic effect on the cardiovascular system, but underlying molecular mechanisms are still not fully understood. The cardiotonic effect always requires abundant energy supplement, which is mainly related to mitochondrial function...