Mechanisms underlying the activity of paederus in hepatocellular carcinoma: A network pharmacology and in vitro validation approach

• Main Authors: Li shan (Author), Duan xiaotong (Author), Wang Qiyi (Author), Liu Jingxian (Author), He Tianmu (Author), Zhang Jianyong (Author), Li Xiaofei (Author)
• Format: Book
• Published: Elsevier, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Paederus, belonging to the Coleoptera and Staphylinidae, can prevent cell mitosis and inhibit tumors. However, few studies exist on the mechanism of Paederus on inhibiting the growth of tumors. Consequently, the present study used network pharmacology, molecular docking and in vitro experiments expl...