Potential Involvement of μ-Opioid Receptor Dysregulation on the Reduced Antinociception of Morphine in the Inflammatory Pain State in Mice

• 主要な著者: Yuta Aoki (著者), Hirokazu Mizoguchi (著者), Chizuko Watanabe (著者), Kumiko Takeda (著者), Tsukasa Sakurada (著者), Shinobu Sakurada (著者)
• フォーマット: 図書
• 出版事項: Elsevier, 2014-01-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

The antinociceptive effect of morphine in the inflammatory pain state was described in the von Frey filament test using the complete Freund's adjuvant (CFA)-induced mouse inflammatory pain model. After an i.pl. injection of CFA, mechanical allodynia was observed in the ipsilateral paw. The anti...