Whole transcriptome analysis reveals differential gene expression profile reflecting macrophage polarization in response to influenza A H5N1 virus infection

• Main Authors: Na Zhang (Author), Yun-Juan Bao (Author), Amy Hin-Yan Tong (Author), Scott Zuyderduyn (Author), Gary D. Bader (Author), J. S. Malik Peiris (Author), Si Lok (Author), Suki Man-Yan Lee (Author)
• Format: Book
• Published: BMC, 2018-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Avian influenza A H5N1 virus can cause lethal disease in humans. The virus can trigger severe pneumonia and lead to acute respiratory distress syndrome. Data from clinical, in vitro and in vivo suggest that virus-induced cytokine dysregulation could be a contributory factor to th...