Liquid biopsy‐based targeted gene screening highlights tumor cell subtypes in patients with advanced prostate cancer

• Glavni autori: Seta Derderian (Autor), Quentin Vesval (Autor), Michel D. Wissing (Autor), Lucie Hamel (Autor), Nathalie Côté (Autor), Marie Vanhuyse (Autor), Cristiano Ferrario (Autor), Franck Bladou (Autor), Armen Aprikian (Autor), Simone Chevalier (Autor)
• Format: Knjiga
• Izdano: Wiley, 2022-11-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Abstract Prostate cancer (PCa) clinical heterogeneity underscores tumor heterogeneity, which may be best defined by cell subtypes. To test if cell subtypes contributing to progression can be assessed noninvasively, we investigated whether 14 genes representing luminal, neuroendocrine, and stem cells...