Immature Brain Cortical Neurons Have Low Transcriptional Competence to Activate Antiviral Defences and Control RNA Virus Infections

• Váldodahkkit: Divya Narayanan (Dahkki), Nagaraj Moily (Dahkki), Hayley A. McQuilten (Dahkki), Katherine Kedzierska (Dahkki), Jason M. Mackenzie (Dahkki), Lukasz Kedzierski (Dahkki), John K. Fazakerley (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Karger Publishers, 2022-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Virus infections of the central nervous system (CNS) cause important diseases of humans and animals. As in other tissues, innate antiviral responses mediated by type I interferons (IFNs) are crucially important in controlling CNS virus infections. The maturity of neuronal populations is an establish...