Iron Oxide Nanoparticles: Selectively Targeting Melanoma Cells In Vitro by Inducing DNA Damage via H2AX Phosphorylation and Hindering Proliferation through ERK Dephosphorylation

• Hoofdauteurs: Danai E. Prokopiou (Auteur), Anastasia Chillà (Auteur), Francesca Margheri (Auteur), Gabriella Fibbi (Auteur), Anna Laurenzana (Auteur), Eleni K. Efthimiadou (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2024-04-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

This study investigates the distinctive characteristics of iron oxide magnetic nanoparticles (mNPs) and their potential application in cancer therapy, focusing on melanoma. Three types of mNPs, pre-validated for safety, underwent molecular analysis to uncover the activated signaling pathways in mela...