MTHFD2-mediated redox homeostasis promotes gastric cancer progression under hypoxic conditions

• Main Authors: Hai-Yu Mo (Author), Ruo-Bing Wang (Author), Meng-Yao Ma (Author), Yi Zhang (Author), Xin-Yu Li (Author), Wang-Rong Wen (Author), Yi Han (Author), Tian Tian (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

ABSTRACTObjectives: Cancer cells undergo metabolic reprogramming to adapt to high oxidative stress, but little is known about how metabolic remodeling enables gastric cancer cells to survive stress associated with aberrant reactive oxygen species (ROS) production. Here, we aimed to identify the key...