ZIKV Infection Induces an Inflammatory Response but Fails to Activate Types I, II, and III IFN Response in Human PBMC

• Main Authors: Francesca Colavita (Author), Veronica Bordoni (Author), Claudia Caglioti (Author), Mirella Biava (Author), Concetta Castilletti (Author), Licia Bordi (Author), Serena Quartu (Author), Marco Iannetta (Author), Giuseppe Ippolito (Author), Chiara Agrati (Author), Maria Rosaria Capobianchi (Author), Eleonora Lalle (Author)
• Format: Book
• Published: Hindawi Limited, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The recent epidemic in the Americas caused by Zika virus (ZIKV), Asian lineage, spurred the research towards a better understanding of how ZIKV infection affects the host immune response. The aim of this study was to evaluate the effects of Asian and East African ZIKV strain infection on the inducti...