The Mitochondrial Na+/Ca2+ Exchanger Inhibitor CGP37157 Preserves Muscle Structure and Function to Increase Lifespan and Healthspan in Caenorhabditis elegans

The Mitochondrial Na+/Ca2+ Exchanger Inhibitor CGP37157 Preserves Muscle Structure and Function to Increase Lifespan and Healthspan in Caenorhabditis elegans

We have reported recently that the mitochondrial Na+/Ca2+ exchanger inhibitor CGP37157 extends lifespan in Caenorhabditis elegans by a mechanism involving mitochondria, the TOR pathway and the insulin/IGF1 pathway. Here we show that CGP37157 significantly improved the evolution with age of the sarco...

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Main Authors: Paloma García-Casas (Author), Pilar Alvarez-Illera (Author), Eva Gómez-Orte (Author), Juan Cabello (Author), Rosalba I. Fonteriz (Author), Mayte Montero (Author), Javier Alvarez (Author)
Format: Book
Published: Frontiers Media S.A., 2021-06-01T00:00:00Z.
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