Prognostic value of absolute quantification of mutated KRAS in circulating tumour DNA in lung adenocarcinoma patients prior to therapy

• Main Authors: Sissel Gyrid Freim Wahl (Author), Hong Yan Dai (Author), Elisabeth F Emdal (Author), Anine L Ottestad (Author), Vibeke G Dale (Author), Elin Richardsen (Author), Tarje O Halvorsen (Author), Bjørn Henning Grønberg (Author)
• Format: Book
• Published: Wiley, 2021-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Droplet digital polymerase chain reaction (ddPCR) is a highly sensitive and accurate method for quantification of nucleic acid sequences. We used absolute quantification of mutated v‐Ki‐ras2 Kirsten rat sarcoma viral oncogene homology gene (KRAS) by ddPCR to investigate the prognostic role...