Increased growth ability and pathogenicity of American- and Pacific-subtype Zika virus (ZIKV) strains compared with a Southeast Asian-subtype ZIKV strain.

• Main Authors: Yasuhiro Kawai (Author), Eri Nakayama (Author), Kenta Takahashi (Author), Satoshi Taniguchi (Author), Ken-Ichi Shibasaki (Author), Fumihiro Kato (Author), Takahiro Maeki (Author), Tadaki Suzuki (Author), Shigeru Tajima (Author), Masayuki Saijo (Author), Chang-Kweng Lim (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We investigated the growth properties and virulence in mice of three Zika virus (ZIKV) strains of Asian/American lineage, PRVABC59, ZIKV/Hu/Chiba/S36/2016 (ChibaS36), and ZIKV/Hu/NIID123/2016 (NIID123), belonging to the three distinct subtypes of this lineage. The American-subtype strain, PRVABC59,...