ITPA, TPMT, and NUDT15 Genetic Polymorphisms Predict 6-Mercaptopurine Toxicity in Middle Eastern Children With Acute Lymphoblastic Leukemia

• Główni autorzy: Borhan Moradveisi (Autor), Samar Muwakkit (Autor), Fatemeh Zamani (Autor), Ebrahim Ghaderi (Autor), Ebrahim Mohammadi (Autor), Nathalie K. Zgheib (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2019-08-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background: Acute lymphoblastic leukemia (ALL) is the most common cancer seen in children worldwide and in the Middle East. Although there have been major advances in treatment approaches for childhood ALL, serious toxicities do occur but with significant inter-individual variability. The aim of thi...