Predictive and prognostic features of early and locally advanced <i>PIK3CA</i>-mutated luminal HER2-negative breast cancer

• Main Authors: A. I. Stukan (Author), T. Yu. Semiglazova (Author), S. I. Kutukova (Author), V. A. Porkhanov (Author), V. N. Bodnya (Author), E. N. Imyanitov (Author), V. V. Antipova (Author), Z. K. Khachmamuk (Author), O. Yu. Chukhray (Author), S. D. Maksimenko (Author)
• Format: Book
• Published: ABV-press, 2024-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Data on the prognostic role of the PIK3CA mutation in hormone receptor-positive (HR+) HER2-negative (HER2-) breast cancer (BC) are contradictory; nevertheless, there are indications of its negative predictive and prognostic significance. This dictates the need for early genetic testing o...