Paneth Cell Ablation Aggravates Pancreatic and Intestinal Injuries in a Rat Model of Acute Necrotizing Pancreatitis after Normal and High-Fat Diet

• Main Authors: Yuecheng Guo (Author), Chunlan Huang (Author), Liyan Liu (Author), Xinyuan Fu (Author), Yingying Lu (Author), Junyuan Zheng (Author), Qixiang Mei (Author), Zehua Huang (Author), Junjie Fan (Author), Lungen Lu (Author), Yue Zeng (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously reported that acute necrotizing pancreatitis (ANP) after normal or high-fat diet is associated with a decreased number of Paneth cells in ileal crypts. Here, we ablated Paneth cells in a rat model of ANP after normal and high-fat diet to investigate the effects on disease symptoms. Adu...