Cryptochrome 1 activation inhibits melanogenesis and melanosome transport through negative regulation of cAMP/PKA/CREB signaling pathway

Cutaneous pigmentation was recently shown to be an event regulated by clock proteins. Cryptochrome (CRY) is a key protein composing the feedback loop of circadian clock, however, the function of CRY in melanocytes remains unclear. Here, we found that KL001, a synthetic small molecule modulator of CR...

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Main Authors: Rongyin Gao (Author), Ximei Zhang (Author), Kun Zou (Author), Duo Meng (Author), Jinpeng Lv (Author)
Format: Book
Published: Frontiers Media S.A., 2023-02-01T00:00:00Z.
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3rd Floor Main Library

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