Cryptochrome 1 activation inhibits melanogenesis and melanosome transport through negative regulation of cAMP/PKA/CREB signaling pathway
Cutaneous pigmentation was recently shown to be an event regulated by clock proteins. Cryptochrome (CRY) is a key protein composing the feedback loop of circadian clock, however, the function of CRY in melanocytes remains unclear. Here, we found that KL001, a synthetic small molecule modulator of CR...
Saved in:
Main Authors: | Rongyin Gao (Author), Ximei Zhang (Author), Kun Zou (Author), Duo Meng (Author), Jinpeng Lv (Author) |
---|---|
Format: | Book |
Published: |
Frontiers Media S.A.,
2023-02-01T00:00:00Z.
|
Subjects: | |
Online Access: | Connect to this object online. |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Similar Items
-
The Inhibitory Effect of Curcumin Derivative J147 on Melanogenesis and Melanosome Transport by Facilitating ERK-Mediated MITF Degradation
by: Jinpeng Lv, et al.
Published: (2021) -
Protoporphyrin IX Stimulates Melanogenesis, Melanocyte Dendricity, and Melanosome Transport Through the cGMP/PKG Pathway
by: Jinpeng Lv, et al.
Published: (2020) -
FGIN-1-27 Inhibits Melanogenesis by Regulating Protein Kinase A/cAMP-Responsive Element-Binding, Protein Kinase C-β, and Mitogen-Activated Protein Kinase Pathways
by: Jinpeng Lv, et al.
Published: (2020) -
Semen Cuscutae flavonoids activated the cAMP-PKA-CREB-BDNF pathway and exerted an antidepressant effect in mice
by: Qianfeng Shao, et al.
Published: (2024) -
<i>Rhynchosia volubilis</i> Promotes Cell Survival via cAMP-PKA/ERK-CREB Pathway
by: Sang-Hyun Ahn, et al.
Published: (2022)