The prostaglandin F synthase activity of the human aldose reductase AKR1B1 brings new lenses to look at pathologic conditions.

• Main Authors: Eva eBresson (Author), Nicolas eLacroix-Péppin (Author), Sofia eBoucher-Kovalik (Author), Pierre eChapdelaine (Author), Michel A Fortier (Author)
• Format: Book
• Published: Frontiers Media S.A., 2012-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prostaglandins are important regulators of female reproductive functions to which aldose reductases exhibiting hydroxysteroid dehydrogenase activity also contribute. Our work on the regulation of reproductive function by prostaglandins (PGs), lead us to the discovery that AKR1B5 and later AKR1B1 wer...