A Recombinant Fusion Construct between Human Serum Albumin and NTPDase CD39 Allows Anti-Inflammatory and Anti-Thrombotic Coating of Medical Devices

• Main Authors: Meike-Kristin Abraham (Author), Elena Jost (Author), Jan David Hohmann (Author), Amy Kate Searle (Author), Viktoria Bongcaron (Author), Yuyang Song (Author), Hans Peter Wendel (Author), Karlheinz Peter (Author), Stefanie Krajewski (Author), Xiaowei Wang (Author)
• Format: Book
• Published: MDPI AG, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Medical devices directly exposed to blood are commonly used to treat cardiovascular diseases. However, these devices are associated with inflammatory reactions leading to delayed healing, rejection of foreign material or device-associated thrombus formation. We developed a novel recombinant fusion p...