Drug Solubility Enhancement through the Preparation of Multicomponent Organic Materials: Eutectics of Lovastatin with Carboxylic Acids

• मुख्य लेखकों: Andrea Mariela Araya-Sibaja (लेखक), José Roberto Vega-Baudrit (लेखक), Teodolito Guillén-Girón (लेखक), Mirtha Navarro-Hoyos (लेखक), Silvia Lucia Cuffini (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: MDPI AG, 2019-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Lovastatin (LOV) is a drug used to treat hypercholesterolemia. Recent studies have identified its antioxidant effects and potential use in the treatment of some types of cancer. However, the low bioavailability related to its poor water solubility limits its use in solid oral dosage forms. Therefore...