Sertaconazole-Nitrate-Loaded Leciplex for Treating Keratomycosis: Optimization Using D-Optimal Design and In Vitro, Ex Vivo, and In Vivo Studies

• Principais autores: Menna M. Abdellatif (Autor), Mina Josef (Autor), Mohamed A. El-Nabarawi (Autor), Mahmoud Teaima (Autor)
• Formato: Livro
• Publicado em: MDPI AG, 2022-10-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

This study aims to develop efficient topical therapy for keratomycosis using sertaconazolenitrate (STZN)-loaded leciplex (LP). The D-optimal design was used to optimize STZN-loaded LP by utilizing soy phosphatidylcholine (SPC) molar ratio (X₁), cationic surfactant molar ratio...