Use of a Chagas Urine Nanoparticle Test (Chunap) to Correlate with Parasitemia Levels in T. cruzi/HIV Co-infected Patients.

• Main Authors: Yagahira E Castro-Sesquen (Author), Robert H Gilman (Author), Carolina Mejia (Author), Daniel E Clark (Author), Jeong Choi (Author), Melissa J Reimer-McAtee (Author), Rosario Castro (Author), Edward Valencia-Ayala (Author), Jorge Flores (Author), Natalie Bowman (Author), Ricardo Castillo-Neyra (Author), Faustino Torrico (Author), Lance Liotta (Author), Caryn Bern (Author), Alessandra Luchini (Author), Chagas/HIV Working Group in Bolivia and Peru (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND:Early diagnosis of reactivated Chagas disease in HIV patients could be lifesaving. In Latin America, the diagnosis is made by microscopical detection of the T. cruzi parasite in the blood; a diagnostic test that lacks sensitivity. This study evaluates if levels of T. cruzi antigens in uri...