Machine learning algorithms to estimate everolimus exposure trained on simulated and patient pharmacokinetic profiles

Abstract Everolimus is an immunosuppressant with a small therapeutic index and large between‐patient variability. The area under the concentration versus time curve (AUC) is the best marker of exposure but measuring it requires collecting many blood samples. The objective of this study was to train...

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Main Authors: Marc Labriffe (Author), Jean‐Baptiste Woillard (Author), Jean Debord (Author), Pierre Marquet (Author)
Format: Book
Published: Wiley, 2022-08-01T00:00:00Z.
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