Intragastric Carbon Dioxide Release Prolongs the Gastric Residence Time of Postprandially Administered Caffeine

• Main Authors: Stefan Senekowitsch (Author), Constantin Foja (Author), Toni Wildgrube (Author), Philipp Schick (Author), Christoph Rosenbaum (Author), Julius Krause (Author), Friederike Brokmann (Author), Marie-Luise Kromrey (Author), Stefan Engeli (Author), Werner Weitschies (Author), Michael Grimm (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Sparkling water is said to increase gastric motility by the release of carbon dioxide, thereby potentially affecting the pharmacokinetics of orally administered drugs. The hypothesis of the present work was that the induction of gastric motility by intragastric release of carbon dioxide from efferve...