Protective effect of the Japanese traditional medicine juzentaihoto on myelosuppression induced by the anticancer drug TS-1 and identification of a potential biomarker of this effect

• Main Authors: Ogawa Kazuo (Author), Omatsu Tatsushi (Author), Matsumoto Chinami (Author), Tsuchiya Naoko (Author), Yamamoto Masahiro (Author), Naito Yuji (Author), Yoshikawa Toshikazu (Author)
• Format: Book
• Published: BMC, 2012-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>TS-1 is an oral anticancer drug containing a 5-fluorouracil derivative (Tegafur) that is widely used in Japan for the treatment of cancer, especially gastrointestinal tumors. Frequently, however, TS-1 therapy has to be discontinued b...