Promoter Methylation of Four Tumor Suppressor Genes in Human Papillary Thyroid Carcinoma

• Main Authors: Fatemeh Khatami (Author), Bagher Larijani (Author), Ramin Heshmat (Author), Shirzad Nasiri (Author), Hiva Saffar (Author), Gita Shafiee (Author), Azam Mossafa (Author), Seyed Mohammad Tavangar (Author)
• Format: Book
• Published: Iranian Society of Pathology, 2019-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background & Objective: Papillary thyroid cancer (PTC) is considered to be the most common type of thyroid malignancies. Epigenetic alteration, in which the chromatin conformation and gene expression change without changing the sequence of DNA, can occur in some tumor suppressor genes and oncoge...