Topical gel based nanoparticles for the controlled release of oleanolic acid: design and in vivo characterization of a cubic liquid crystalline anti-inflammatory drug

• Hoofdauteurs: Zhiqi Shi (Auteur), Shugang Pan (Auteur), Luolin Wang (Auteur), Sha Li (Auteur)
• Formaat: Boek
• Gepubliceerd in: BMC, 2021-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Abstract Background Oleanolic acid (OA) has multiple pharmaceutical applications including anti-inflammatory activity, but low permeability of the molecule limits its widespread use. Methods A cubic liquid crystalline nanoparticle (LCNP)-based gel was prepared as a potential topical delivery system...