Development and validation of a quantitative electron microscopy score to assess acute cellular stress in the human exocrine pancreas

• Main Authors: Nicole Kattner (Author), Nicola Dyson (Author), Yvonne Bury (Author), Dina Tiniakos (Author), Kathryn White (Author), Tracey Davey (Author), Lena Eliasson (Author), Lynn Tindale (Author), Bart E Wagner (Author), Minna Honkanen‐Scott (Author), Jennifer Doyle (Author), Rutger J Ploeg (Author), James AM Shaw (Author), William E Scott III (Author)
• Format: Book
• Published: Wiley, 2021-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract The pancreas is particularly sensitive to acute cellular stress, but this has been difficult to evaluate using light microscopy. Pancreatic ischaemia associated with deceased organ donation negatively impacts whole‐organ and isolated‐islet transplantation outcomes. Post‐mortem changes have...