Automated Radiosynthesis of [¹⁸F]FluoFAPI and Its Dosimetry and Single Acute Dose Toxicological Evaluation

• Main Authors: Jason A. Witek (Author), Allen F. Brooks (Author), Sahil M. Kapila (Author), Wade P. Winton (Author), Jenelle R. Stauff (Author), Peter J. H. Scott (Author), Benjamin L. Viglianti (Author)
• Format: Book
• Published: MDPI AG, 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: Cancer-associated fibroblasts have become a new target for therapy. Fibroblasts present within malignancies express the fibroblast activation protein (FAP). Inhibitors to FAP (FAPI) are small molecules recently developed as a theranostic agents for imaging and radiotherapy. All currently...