Automated Radiosynthesis of [¹⁸F]FluoFAPI and Its Dosimetry and Single Acute Dose Toxicological Evaluation

• Главные авторы: Jason A. Witek (Автор), Allen F. Brooks (Автор), Sahil M. Kapila (Автор), Wade P. Winton (Автор), Jenelle R. Stauff (Автор), Peter J. H. Scott (Автор), Benjamin L. Viglianti (Автор)
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• Опубликовано: MDPI AG, 2024-06-01T00:00:00Z.
• Предметы: article
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Background: Cancer-associated fibroblasts have become a new target for therapy. Fibroblasts present within malignancies express the fibroblast activation protein (FAP). Inhibitors to FAP (FAPI) are small molecules recently developed as a theranostic agents for imaging and radiotherapy. All currently...