Role of Glucocorticoid Receptor in the Regulation of Cellular Sensitivity to Irinotecan Hydrochloride

• Main Authors: Takanori Akagi (Author), Tatsuo Fukagawa (Author), Yuki Kage (Author), Hideto To (Author), Naoya Matsunaga (Author), Satoru Koyanagi (Author), Akiko Uchida (Author), Asuka Fujii (Author), Hideo Iba (Author), Toshimichi Ikemura (Author), Hironori Aramaki (Author), Shun Higuchi (Author), Shigehiro Ohdo (Author)
• Format: Book
• Published: Elsevier, 2009-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In clinical practice, glucocorticoids are often used with the aim of modulating the efficacy and toxicity of chemotherapeutic agents. However, how glucocorticoids modulate the pharmacological action of chemotherapeutic agents remains to be clarified. In this study, we generated glucocorticoid recept...