Effects of membrane transport activity and cell metabolism on the unbound drug concentrations in the skeletal muscle and liver of drugs: A microdialysis study in rats
Abstract The unbound concentrations of 14 commercial drugs, including five non‐efflux/uptake transporter substrates-Class I, five efflux transporter substrates-class II and four influx transporter substrates-Class III, were simultaneously measured in rat liver, muscle, and blood via microanalysis. K...
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| Main Authors: | , , , , , , , , , , , |
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| Format: | Book |
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Wiley,
2021-10-01T00:00:00Z.
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