Fasciola hepatica serine protease inhibitor family (serpins): Purposely crafted for regulating host proteases.

• Main Authors: Carolina De Marco Verissimo (Author), Heather L Jewhurst (Author), Irina G Tikhonova (Author), Rolf T Urbanus (Author), Aaron G Maule (Author), John P Dalton (Author), Krystyna Cwiklinski (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Serine protease inhibitors (serpins) regulate proteolytic events within diverse biological processes, including digestion, coagulation, inflammation and immune responses. The presence of serpins in Fasciola hepatica excretory-secretory products indicates that the parasite exploits these to regulate...