Overexpression of Ubiquitin-Specific Protease 2 (USP2) in the Heart Suppressed Pressure Overload-Induced Cardiac Remodeling

• Main Authors: Junhui Xing (Author), Pengcheng Li (Author), Jin Hong (Author), Mengyu Wang (Author), Yuzhou Liu (Author), Yueqiao Gao (Author), Jianzeng Dong (Author), Heping Gu (Author), Ling Li (Author)
• Format: Book
• Published: Hindawi Limited, 2020-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Ubiquitin-specific protease 2 (USP2) is an important member of the deubiquitination system. GEO dataset revealed that USP2 was downregulated in the hearts under pressure overload. However, the cardiomyocyte-specific function of USP2 in the setting of pressure overload is unknown. In the current stud...