Clinical Trial Simulation To Optimize Trial Design for Fludarabine Dosing Strategies in Allogeneic Hematopoietic Cell Transplantation

• Príomhchruthaitheoirí: Jurgen B. Langenhorst (Údar), Thomas P.C. Dorlo (Údar), Charlotte vanKesteren (Údar), Erik M. vanMaarseveen (Údar), Stefan Nierkens (Údar), Moniek A. deWitte (Údar), Jaap Jan Boelens (Údar), Alwin D.R. Huitema (Údar)
• Formáid: LEABHAR
• Foilsithe / Cruthaithe: Wiley, 2020-05-01T00:00:00Z.
• Ábhair: article
• Rochtain ar líne: Connect to this object online.

Optimal fludarabine exposure has been associated with improved treatment outcome in allogeneic hematopoietic cell transplantation, suggesting potential benefit of individualized dosing. A randomized controlled trial (RCT) comparing alternative fludarabine dosing strategies to current practice may be...