Inosine induces acute hyperuricaemia in rhesus monkey (Macaca mulatta) as a potential disease animal model

• Main Authors: Dong-hong Tang (Author), Chen-yun Wang (Author), Xi Huang (Author), Hong-kun Yi (Author), Zhe-li Li (Author), Kai-li Ma (Author), You-song Ye (Author), Jian-wen Zhang (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Context The uric acid metabolism pathway is more similar in primates and humans than in rodents. However, there are no reports of using primates to establish animal models of hyperuricaemia (HUA). Objectives To establish an animal model highly related to HUA in humans. Materials and methods Inosine...